The Ethics of Genetic Control: Ending Reproductive Roulette

of hippicampal pathology in temporal lobe epilepsy, i.e. the abnormal tissues extirpated. This landmark work indicates the extensive abnormalities appearing in the dendrites of the involved neurons, and of the glia, confirming, in man, findings previously shown in certain experimental models of epileptogenic foci. These suggest an ongoing, repeated, progressive process in such epileptic brains and open up new areas of thought and possibilities for research. Jann Brown then gives his descriptions of structural substrates of seizure foci in the removed human temporal lobes of this series, utilizing optical, microscopic, and ultrastructural techniques. The distribution of lesions, with over 50% mesial temporal sclerosis and 24% hamartoma is confirmatory of the work of Falconer and his group, in London. The ultrastructural studies of hippocampus show interesting lesions of both dendrites, and axonal structures. Throughout this work there is the "shade" of John Fulton, the eminent Yale neurophysiologist, who first designated the form of temporal lobe epilepsy as really "limbic," in 1953. The book is beautifully published, with excellent figures and extensive reference lists after each section. It should be read by all interested in, and concerned with, the major problem of epilepsy in man. Not everyone will agree with everything, but this is a stimulating volume, and a measure of clear progress, giving us a distinct look into the future.